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    Trank1 tetratricopeptide repeat and ankyrin repeat containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 316022, updated on 4-Apr-2024

    Summary

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    Official Symbol
    Trank1provided by RGD
    Official Full Name
    tetratricopeptide repeat and ankyrin repeat containing 1provided by RGD
    Primary source
    RGD:1563130
    See related
    Ensembl:ENSRNOG00000021091 AllianceGenome:RGD:1563130
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563130
    Summary
    Orthologous to human TRANK1 (tetratricopeptide repeat and ankyrin repeat containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 240.4), Testes (RPKM 172.6) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    8q32
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (120153381..120233879)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (111275973..111355491)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (119566509..119644249)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene mutL homolog 1 Neighboring gene EPM2A interacting protein 1 Neighboring gene U2 spliceosomal RNA Neighboring gene doublecortin-like kinase 3 Neighboring gene uncharacterized LOC108351782

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    TPR and ankyrin repeat-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191799.3 → NP_001178728.1  TPR and ankyrin repeat-containing protein 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6I3J3, D3ZSG2
      Related
      ENSRNOP00000028633.6, ENSRNOT00000028633.6
      Conserved Domains (6) summary
      cd00204
      Location:540 → 662
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00006
      Location:144 → 172
      TPR; TPR repeat [structural motif]
      pfam12796
      Location:541 → 654
      Ank_2; Ankyrin repeats (3 copies)
      pfam13414
      Location:144 → 207
      TPR_11; TPR repeat
      sd00045
      Location:540 → 567
      ANK; ANK repeat [structural motif]
      cl21455
      Location:1391 → 1498
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      120153381..120233879
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039081618.2 → XP_038937546.1  TPR and ankyrin repeat-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      A6I3J3
      Conserved Domains (5) summary
      PHA03095
      Location:271 → 412
      PHA03095; ankyrin-like protein; Provisional
      COG0210
      Location:1468 → 1721
      UvrD; Superfamily I DNA or RNA helicase [Replication, recombination and repair]
      COG0666
      Location:447 → 631
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00006
      Location:105 → 133
      TPR; TPR repeat [structural motif]
      sd00045
      Location:502 → 529
      ANK; ANK repeat [structural motif]

    2. XM_039081614.2 → XP_038937542.1  TPR and ankyrin repeat-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A6I3J3
      Conserved Domains (6) summary
      PHA03381
      Location:22 → 219
      PHA03381; tegument protein VP22; Provisional
      PHA03095
      Location:310 → 451
      PHA03095; ankyrin-like protein; Provisional
      COG0210
      Location:1507 → 1760
      UvrD; Superfamily I DNA or RNA helicase [Replication, recombination and repair]
      COG0666
      Location:486 → 670
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00006
      Location:144 → 172
      TPR; TPR repeat [structural motif]
      sd00045
      Location:541 → 568
      ANK; ANK repeat [structural motif]

    3. XM_039081617.2 → XP_038937545.1  TPR and ankyrin repeat-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      A6I3J3
      Conserved Domains (6) summary
      PHA03381
      Location:22 → 219
      PHA03381; tegument protein VP22; Provisional
      PHA03095
      Location:310 → 449
      PHA03095; ankyrin-like protein; Provisional
      COG0210
      Location:1501 → 1754
      UvrD; Superfamily I DNA or RNA helicase [Replication, recombination and repair]
      COG0666
      Location:480 → 664
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00006
      Location:144 → 172
      TPR; TPR repeat [structural motif]
      sd00045
      Location:535 → 562
      ANK; ANK repeat [structural motif]

    4. XM_039081615.2 → XP_038937543.1  TPR and ankyrin repeat-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A6I3J3
      Conserved Domains (6) summary
      PHA03381
      Location:22 → 219
      PHA03381; tegument protein VP22; Provisional
      PHA03095
      Location:309 → 450
      PHA03095; ankyrin-like protein; Provisional
      COG0210
      Location:1506 → 1759
      UvrD; Superfamily I DNA or RNA helicase [Replication, recombination and repair]
      COG0666
      Location:485 → 669
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00006
      Location:144 → 172
      TPR; TPR repeat [structural motif]
      sd00045
      Location:540 → 567
      ANK; ANK repeat [structural motif]

    5. XM_039081616.2 → XP_038937544.1  TPR and ankyrin repeat-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A6I3J3
      Conserved Domains (6) summary
      PHA03381
      Location:22 → 219
      PHA03381; tegument protein VP22; Provisional
      PHA03095
      Location:308 → 449
      PHA03095; ankyrin-like protein; Provisional
      COG0210
      Location:1505 → 1758
      UvrD; Superfamily I DNA or RNA helicase [Replication, recombination and repair]
      COG0666
      Location:484 → 668
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00006
      Location:144 → 172
      TPR; TPR repeat [structural motif]
      sd00045
      Location:539 → 566
      ANK; ANK repeat [structural motif]

    RNA

    1. XR_005487854.2 RNA Sequence

    2. XR_005487855.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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